| Date | Location | Result | |
| 3/11/06 | Neal Fieldhouse; Greencastle, Indiana | Hope College 76, DePauw University 60 | Box score |
| 3/10/06 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 69, Wheaton College 60 | Box score |
| 3/10/06 | Neal Fieldhouse; Greencastle, Indiana | Hope College 92, Washington University 89 | Box score |
| 3/4/2006 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 86, Maryville (Tenn.) College 58 | Box score |
| 02/26/06 | Memphis, Tenn. - Mallory-Hyde Gymnasium | DePauw University 67, Trinity University 65 | Box score |
| 02/25/06 | Memphis, Tenn. - Mallory-Hyde Gymnasium | DePauw University 89, Rhodes College 73 | Box score |
| 02/24/06 | St. Benedict at Auburndale | DePauw University 80, Millsaps Women 61 | Box score |
| 2/18/06 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 72, Rose-Hulman 61 | Box score |
| 2/12/06 | Sewanee, Tenn. (Juhan Gymnasium) | DePauw University 79, Sewanee 51 | Box score |
| 2/10/06 | Danville, KY | DePauw University 83, Centre College 31 | Box score |
| 2/5/06 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 69, Rhodes College 64 | Box score |
| 2/3/06 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 103, Hendrix College 85 | Box score |
| 1/29/06 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 60, Trinity (Texas) 57 | Box score |
| 1/27/06 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 87, Southwestern (Tex.) 61 | Box score |
| 1-22-06 | Atlanta, GA | DePauw University 88, Oglethorpe University 60 | Box score |
| 01/20/06 | Jackson, MS (The Hanger) | DePauw University 76, Millsaps College 47 | Box score |
| 1/15/06 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 106, Sewanee 66 | Box score |
| 1/13/06 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 85, Centre College 39 | Box score |
| 01/07/06 | Hulbert Arena - Terre Haute, Ind. | DePauw 87, Rose-Hulman 64 | Box score |
| 12/31/05 | Grand Canynon University | DePauw University, IN 87, William Paterson Univ., NJ 56 | Box score |
| 12/29/05 | Grand Canyon University | DePauw University, IN 84, Viterbo University, WI 33 | Box score |
| 12/28/05 | Grand Canyon University | DePauw University, IN 76, Lewis and Clark College, OR 63 | Box score |
| 12/21/05 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 84, Webster University 44 | Box score |
| 12/17/05 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 85, Wittenberg University 70 | Box score |
| 12/10/05 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 94, William Woods University 56 | Box score |
| 12/4/05 | Mallory Gym | DePauw University 65, Rhodes College 64 | Box score |
| 12/02/05 | Conway, AR | DePauw University 76, Hendrix College 66 | Box score |
| 11/27/05 | Wilmington College | DePauw University 88, Wilmington College 75 | Box score |
| 11/26/05 | Wilmington College | DePauw University 78, Hanover College 47 | Box score |
| 11-23-05 | St.Louis | DePauw University 72, Fontbonne 53 | Box score |
| 11-19-05 | St. Louis, Mo. (WU Field House) | Washington University 72, DePauw University 61 | Box score |
| 11-18-05 | St. Louis, Mo. (WU Field House) | DePauw University 72, Illinois Wesleyan University 60 | Box score |